
Matthew Peter Holtzman, MD
Surgical Oncology
General Surgery
Highlights
Age Groups Seen
- Adult
- Older Adult
Languages
- English
In-Network Plans
View All Accepted Plans (21)Gender
MaleAbout Matthew Peter Holtzman
Matthew Holtzman, MD, is a surgical oncologist specializing in the treatment of colorectal, liver, GI cancers, as well as melanoma and sarcoma. In addition to traditional surgery, Dr. Holtzman specializes in Minimally Invasive surgical approaches to cancer treatment. As part of the David C. Koch Regional Perfusion Cancer Therapy Center, Dr. Holtzman's team performs many specialized concentrated regional chemotherapy and radiotherapy procedures to treat advanced malignancies. His research interests include the treatment of recurrent cancers, regional radiation therapies, and novel treatments for melanoma.
Dr. Holtzman received his medical degree from the State University of New York Health Science Center at Brooklyn in 1999, where he graduated Magna Cum Laude. His residence was performed at Boston University's Department of Surgery in Boston. He completed a Surgical Oncology fellowship at UPMC and remained on faculty since 2006.
Dr. Holtzman is a member of professional organizations, including the American College of Surgeons, American Society of Clinical Oncology, Massachusetts Medical Society, and the Society of Surgical Oncology.
This provider is affiliated with UPMC.

Provider Type
Physician
Locations
- MWH HBC HILLMAN CCr Center
- 5115 Centre Avenue, HILLMAN CANCER CENTER, Floor 2, Pittsburgh, PA 15232
- phone: 412-692-2852
Expertise
Education
University of Pittsburgh School of Medicine
FellowshipBoston Medical Center
ResidencySUNY Downstate Medical Center
Medical EducationBoard Certifications
Surgery
American Board of SurgeryInsurance
- UPMC for Life
- UPMC for You
- UPMC Health Plan
- Aetna
- Amerihealth Caritas
- Cigna
- Gateway
- Highmark
- Humana
- Independent Health
- Medical Mutual of OH
- Medicare
- Non-PA Medical Assistance
- PA Health And Wellness
- PA Medical Assitance
- Palmetto
- The Health Plan
- Tricare
- Unison
- United Healthcare
- Veterans Choice
Ratings & Reviews
4.8 out of 5
121 ratings, 27 reviewsThe Patient Satisfaction Rating is an average of all responses to the care provider related questions shown below from our survey. Patients that are treated in outpatient or hospital environments may receive different surveys, and the volume of responses will vary by question.
- 5 out of 5 starsReviewed on 3/12/2025
Good
- 5 out of 5 starsReviewed on 2/26/2025
I love them just met them and love them
- 5 out of 5 starsReviewed on 2/5/2025
I was very pleased with the care I received and felt more comfortable about my health concerns than when I arrived
- 5 out of 5 starsReviewed on 2/5/2025
Dr Holtzman listened and explained my condition and offered treatment both surgical and otherwise. I appreciated his concern and approach to my situation.
- 5 out of 5 starsReviewed on 2/5/2025
I was seen by the PA (Angela Schandelmeier) and Dr. Matthew Holtzman. Both visits were and always are, GREAT! They always are so welcoming and are geniunely concerned about my well being. They both take the time to really listen and answer any and all questions/concerns I have.
- 5 out of 5 starsReviewed on 1/29/2025
Very personable and very professional. Great experience overall
- 5 out of 5 starsReviewed on 1/29/2025
Dr holtzman is very kind, and knowledgeable about my surgery and cares a lot about concerns
- 5 out of 5 starsReviewed on 1/29/2025
Dr Holtzman is amazing
- 5 out of 5 starsReviewed on 1/22/2025
Both doctors were very thorough and thoughtful in discussing my hernia and asking questions. They each showed a real interest in my health.
- 5 out of 5 starsReviewed on 1/8/2025
Everyone did a fine job .
- 5 out of 5 starsReviewed on 12/18/2024
Great experience
- 5 out of 5 starsReviewed on 10/30/2024
It went very well on everything.
- 5 out of 5 starsReviewed on 10/16/2024
Dr Holtzman is the best.Angela ? Name. PA was very good also
- 5 out of 5 starsReviewed on 10/9/2024
All info requested was provided and explained very well in
- 5 out of 5 starsReviewed on 10/2/2024
Treated so well since I screwed up the appointment a day earlier.
- 5 out of 5 starsReviewed on 9/25/2024
staff was knowledgeable, kind, caring, and took their time explaining and answering questions
- 5 out of 5 starsReviewed on 9/25/2024
DR Holtzman a wonderful caring person. Best compliment is I trust him with my life.
- 5 out of 5 starsReviewed on 9/18/2024
Dr.Holtzman and his associate was very forthcoming with my problem and with the surgery that was going to happen....
- 5 out of 5 starsReviewed on 8/28/2024
We have already recommended Dr. Holtzman, in high regards, to others, and our friends and family!
- 5 out of 5 starsReviewed on 8/28/2024
Dr. Holtzman and his PA were wonderful!
- 5 out of 5 starsReviewed on 7/24/2024
This surgery Is a challenging thing to recover from because it is mostly painless. So not much to guide me there. It has to be cognitive, think before you do! We had a good discussion about what can be done in the future at the right time. And also what to be doing , and not doing now. Very very helpful and reassuring
- 5 out of 5 starsReviewed on 7/17/2024
All were very good, and both doctors (Holtsman & assit) covered all of my questions and concerns
- 5 out of 5 starsReviewed on 7/3/2024
Good
- 5 out of 5 starsReviewed on 6/26/2024
I would highly recommend this practice
- 5 out of 5 starsReviewed on 6/5/2024
Excellent
- 5 out of 5 starsReviewed on 5/29/2024
Excellent
- 5 out of 5 starsReviewed on 5/8/2024
Dr. Holtzman and his associate were very professional, courteous, kind, and caring. Dr. Holtzman is exceptional at explaining what you need, answering all of your questions, and he really listens to his patients - even stating that all extra information is appreciated because it helps him understand more about why things happened and what is needed for treatment. That is exceptional in a Dr. His intelligence, exceptional knowledge in his & other fields, and his uncanny ability to help everyone understand their bodies, their health status, and their ability to heal, lifts him a step above many.